General Information

  • ID:  hor002562
  • Uniprot ID:  A0A7M7GM99
  • Protein name:  Neuropeptide like precursor 1
  • Gene name:  LOC100577694
  • Organism:  Apis mellifera (Honeybee)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  YVASLARTGDLPIRGQ
  • Length:  16
  • Propeptide:  MVEMAYIRKLTRTLPVLRFGEPHWEDISDLVCEMGLTGNHLVTLLLYVAVVNEIRLPLVTCQDEDSTQCMPKTAFLALLRHPEVSSSLAAYSRAARVTQDTKSRNDMAHLRALTEEGDDTEICVPGRVYLQLLKDPVVRGDLSAILNGRTQKVPDLLGRLIDDTDQMDAREYPFEYQKRSIATLAKNDDLPISLHDRMAENEDDEEKRAVISSSDHSIIRDYLPPNGRSEEQALRDFSMEKRNVGTLARDFALPPGRRNIASLMRDYDQSRENRVPFPGKRNVASLARTYTLPQNAGKRNVGSVAREHGLPYGKRYVASLARTGDLPIRGQRSVSSLARTGDLPVREQRSVSSLAKNSAWPVSLKRGIFLPGSVILRALSRQGRSFDSADTNARNDLLDLQALGNLRQSQENDYESEEKVNDSLKADSNIRRSKREIAFSDEYPLPVMQNANMFDYEEMMEALGGQYPNAEKRFMGTGSAPEMQPEVDQFGYPETFQANKRHIGALARLGWLPSLRTARFSRSPRYLVDRENPADGSSPNYSSNSSTRSLRPNLNPRTRYIQALHGDCRHGFKRFLLLPATDNNYFHQKLPSSLRSKSL
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7GM99-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002562_AF2.pdbhor002562_ESM.pdb

Physical Information

Mass: 198470 Formula: C75H125N23O23
Absent amino acids: CEFHKMNW Common amino acids: AGLR
pI: 9.35 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 6
Hydrophobicity: -8.13 Boman Index: -2591
Half-Life: 2.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: 2 min Aliphatic Index 103.75
Instability Index: 1080 Extinction Coefficient cystines: 1490
Absorbance 280nm: 99.33

Literature

  • PubMed ID:  19576913
  • Title:  Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera